Determination of Diethylene Glycol in Toothpaste
نویسندگان
چکیده
منابع مشابه
A Greener Way to Screen Toothpaste for Diethylene Glycol
A method developed for the screening of diethylene glycol (DEG) in toothpaste was released by the FDA in 2007. This method could not only quantify the DEG but also confirm if any potential interfering peak is present. However, disadvantages of this method such as intermittent shortages of the key reagent acetonitrile and the shorter than expected column-life issues have prompted a search for al...
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A rapid method for determining diethylene glycol (DEG) in toothpaste based on the use of ultra-performance liquid chromatography (UPLC) coupled to time-of-flight mass spectrometry (TOF-MS) has been developed. The method has been validated in toothpaste samples spiked at different levels, 0.005, 0.1 and 5%, obtaining satisfactory recoveries (74-98%) and relative standard deviations (<4%). Quanti...
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A simple, rapid, and reliable method was developed for the quantitative determination of diethylene glycol (DEG) in pharmaceutical products using capillary gas chromatography with flame ionization detection. The method uses ethylene glycol as internal standard and allows for the separation of propylene glycol and DEG. The assay was linear in a DEG concentration range between 1.0 and 10.00 mg/mL...
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The aim of the present study was to investigate the hepatotoxic effects of accidental intravenous diethylene glycol (DEG) poisoning in patients with liver disease. Clinical manifestations were recorded and liver function tests were carried out for 64 patients with liver disease who had been accidentally treated intravenously with DEG. Comparisons were made between the poisoned and non-poisoned ...
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ژورنال
عنوان ژورنال: Journal of Society of Cosmetic Chemists of Japan
سال: 2008
ISSN: 1884-4146,0387-5253
DOI: 10.5107/sccj.42.36